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As an NNMT inhibitor, its shown promise in models targeting insulin sensitivity, lipid oxidation, and age-related metabolic decline

However, more research is needed to support these claims

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The AFBO is highly unstable, and it reacts with cellular nucleophiles and can induce mutations by alkylating DNA, principally at the N 7 position of guanine forming the 8,9-dihydro- 8-(N 7 -guanyl)-9-hydroxy-AFB 1

Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors