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For instance, Beatty notes that the clinical diagnostic maneuver used by Filler et al

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The effectiveness period of these injections varies based on individual factors and metabolism rates, and may last between one to two weeks in the system [12]

However, there are established patterns based on clinical observations

4,5 Dietary insufficiency, pernicious anemia (i.e., an autoimmune process that reduces available intrinsic factor and subsequent absorption of vitamin B 12 1,2,6,7 ), and long-term use of metformin or acid-suppressing medications have been implicated in B 12 deficiency

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