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miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT1 in melanoma

Numerous preclinical studies with pharmacological Nrf2 activators (e.g., sulforaphane, naringenin, curcumin) have demonstrated significant cardioprotection in MIRI models, attenuating injury, reducing infarct size, and decreasing oxidative stress, inflammation, and cell death (Wang R

cytosolic reduction
Lipoxygenases and non-enzymatic reactions instead lead to the production of the most harmful products of LPO, namely hydroperoxides

doi: 10.1067/mjd.2003.425

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