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Hamm-Faber TE, Aukes H, van Gorp EJ, Gltuna I

One of the reasons many calorie restriction diets are so ineffective in producing weight loss for some is because the human body naturally wants to adjust to the reduced calories by also reducing metabolism

Pernicious anemia may arise from gastrointestinal disorders such as Crohn's disease or from surgeries and genetic mutations that disrupt intrinsic factor production

These include oral leptin mimetics and intranasal leptin, both of which are in preclinical stages of drug development [15,45,46]

Miyanari, Y
