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This ligand-receptor binding propagates the signal transduction in melanocytes via adenylcyclase, protein kinase A (PKA), and cyclic AMP response element binding protein (CREB) to ultimately upregulate MiTF expression

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A recent study found that COL11A1 activated Src-Akt-AMPK signal transduction by binding to 11 integrin and discoidin domain receptor 2 to up-regulate FAO, making ovarian cancer (OC) cells resistant to cisplatin [64]

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A., Newton, R

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Fat-dissolving injections that are not FDA approved can be harmful

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doi:10.1016/j.steroids.2011.12.001 Thavaraputta S, Dennis JA, Laoveeravat P, Nugent K, Rivas AM

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