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Mutant isocitrate dehydrogenase 1/2 (IDH1/2) produces the oncometabolite 2-hydroxyglutarate (2-HG), which inhibits -KGdependent dioxygenases, resulting in widespread epigenetic dysregulation [98-100]

The peptide functions as a biological signal that resets gene expression patterns toward a healthier, more youthful state

This paper was not cited in the literature until 2009, and was, interestingly, cited in the context of the potential importance of vaccines, not APAP, in the etiology of ASD [60]

doi: 10.1002/jcp.28134

Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

[Google Scholar] Wang Z., Wang X., Mou X., Wang C., Sun Y., Wang J