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Sardi et al., 2015)

It is also important for brain and nerve cell function and development

In the case of LPA signaling, downstream effectors such as PI3K, MAPK, and Rho GTPase orchestrate critical cellular functions, including proliferation, migration, and survival, mirroring the layered architecture of neural networks that process inputs across multiple nodes to derive complex outputs

Sestrin2 regulates monocyte activation through AMPK-mTOR nexus under high-glucose and dyslipidemic conditions

translating these findings to the complex clinical heterogeneity of human MDD requires further validation through human studies

Such a role is likely to have a mechanistic impact on the process of carcinogenesis and offer possible therapeutic potentials