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Not if you ask our customers, who self-inject our methyl B12 on a daily basis

If symptoms are severe enough to disrupt daily function, reduce the dose to 2550mg for 57 days, then re-escalate slowly

The gap between doing this work correctly and wasting months of effort comes down to understanding what the evidence base actually contains versus what supplement marketing claims it contains

Omega-3 (orthomega 820) While most fish oil supplements are delivered in ethyl ester form, the Orthomega delivers ultra-pure, high concentration fish oil ONLY in preferred triglyceride for, with superior absorption Probiotics (Ortho biotic 100) Ortho Biotic 100 is a high dose probiotic delivering 100 billion active cultures for intensive GI and immune support

In higher dose supplements, that percentage drops to 1%-2%
