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[1] Vitamin B 12 deficiency, which is reversible, is occasionally confused with acute myeloid leukemia, which is an irreversible condition presenting with some of the same hematological symptoms, including hypercellular bone marrow with blastic differentiation and hypersegmented neutrophils

Hepcidin inhibits the absorption of iron from the intestines and hinders the recovery of iron from the breakdown of red blood cells (see Chapter 4)

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Without adequate B12, DNA synthesis falters, producing enlarged, dysfunctional red blood cells characteristic of megaloblastic anemia

Because Vitamin B12 is tied so closely to the bodys metabolic processes and neurological function, Physique26 treats it as a measurable lever

Pernicious Anemia: The Lifelong Commitment For anyone diagnosed with pernicious anemia , the question of "how often should I get B12 shots?" has a straightforward answer: for life