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Furthermore, a diet high in saturated fat and sugars is linked to a more severe course of schizophrenia (133)

Trx catalyzes the thiol-disulfide exchange reaction, which involves electron transfer between Trx and its target protein

We do not provide scaffold split 20 , popular in medicinal chemistry, for the following reasons

The crosstalk between NRF2 and NF-B signaling pathways has been demonstrated after the administration of isoflavones in a mouse model of chronic sleep deprivation

The importance of the strictly conserved lysyl residue for the function of both classes of Grxs has been addressed before

Water allows hydrolysis, deamidation, and microbial activity to proceed much faster