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The continuous production of ONOO could suppress the activity of glutathione reductase by nitration modification, thus collectively reducing detoxification and blocking DNA damage repair

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[50] [48] The number of published studies on the role of pulmonary rehabilitation in idiopathic pulmonary fibrosis is small, but most of these studies have found significant short-term improvements in functional exercise tolerance, quality of life, and dyspnea on exertion

Glutathione: A Key Player in Autoimmunity

In paired sets of mice (i.e., mice which had been subjected to TBI or Sham surgery on the same day), Iba1 immunoreactivity was increased in the brains of untreated TBI mice in comparison to both Sham control mice and Immunocalpretreated mice subjected to TBI (Figure 9A)