melanotan org Frontiers Melanotan 2 | Cyclic Heptapeptide

TNF induces BRN2 signaling (87) and, in line with often mutually exclusive expression of BRN2 and MITF, it has been identified as an inhibitor of MITF and Melan A in 40 different melanoma cell lines (86)

Not approved by the MHRA for human use

Nature 581 , 329332 (2020)

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Difficulties are sometimes experienced in differentiating invasive melanoma (particularly the nevoid and small cell variants) from residual benign intradermal nevus cells