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Creatine and its potential therapeutic value for targeting cellular energy impairment in neurodegenerative diseases

doi: 10.12816/0031237

The uniform manifold approximation and projection plot identifies nine major cell types, with excitatory neurons dominating gray matter voxels (high OXPHOS demand) and oligodendrocyte precursor cells enriched in white matter (Fig

Seid, M

40.1 14.2 years)

It is reported that 17-estradiol (E2) could suppress the TGF1-induced myofibroblast transformation and reduce the collagen production by inhibiting the TGF-1/SMAD and Rho/RhoA signaling pathway ( On the other hand, the role of adenosine receptors in transformation from fibroblast to myofibroblast in PD was investigated recently