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It blocks tyrosinase, the enzyme required to produce melanin

Conclusions Our study is the first to identify the specific role of SIRT2 in reactive astrogliosis and determine the specific pathway and metabolic step catalyzed by the enzyme

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This process serves to regulate the promoterenhancer activity, particularly those involving superenhancers, thereby enhancing the transcription of pluripotencyregulating genes and ultimately supporting the maintenance of pluripotency