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This layer of endothelial cells acts as a sensor that integrates and conveys signals from the blood and surrounding tissue, ultimately influencing the contraction of vascular smooth muscle

2136%) settings and it may contribute to urban MetS due to unfavorable lifestyle choices, higher socioeconomic class, lesser physical exercise, increased stress, and excessive salt and red meat consumption (8)

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hemoglobin SS), complicated by chronic anemia with a baseline hemoglobin of 6 to 7 g/dL and significantly elevated hemolysis markers, alloimmunization, iron overload, dilated cardiomyopathy with preserved ejection fraction, cholelithiasis requiring cholecystectomy, and occasional acute pain episodes presents to an outpatient clinic for follow-up

The mitochondrial transcription factor A (TFAM) mRNA carried by MSC-EVs can alleviate mitochondrial damage and inflammation by stabilizing mtDNA (Zhao et al., 2021)