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These results showed a significant change in serum globulin levels among all the groups (Table 4)

Hager AS, Wolter A, Czerny M, Bez J, Zannini E, Arendt EK, Czerny M

Under the influence of adverse factors of various nature (physical, chemical, biological, etc.) or the presence of systemic or local pathology, the imbalance between the excessive generation of these oxidants and the activity of their detoxification by enzymatic and nonenzymatic antioxidant systems form a special pathological conditionoxidative stress [68,69,70,71]

Specifically, intestinal barrier disruption leads to microbiota translocation and endotoxinemia, triggering hepatic immune cell activation and the secretion of inflammatory cytokines, which can further exacerbate hepatic injury [162]

doi: 10.1084/jem.20140857 95 MattsonM

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