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Elevated expression of GPx1 was also associated with poor survival for other cancers, including oral squamous cell carcinoma [138], acute myeloid leukemia [139], gliomas [140], and invasive ductal cell carcinoma [141]

They affect amyloidosis through their role in the synthesis and disposal of A, as well as through interactions with other CNS cells (Liddelow et al., 2017

Abnormal mechanical stress is a critical factor in the development of disc degeneration

Impaired mitochondrial respiration (Weinberg & Humes, 1980) and decreased incorporation of leucine into microsomal protein (Bennett et al., 1988) have also been observed prior to the onset of obvious irreversible cell injury

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