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The lower level of renal L-arginine in SS rats might result, in part, from fumarase insufficiency and the subsequent reduction of L-arginine regeneration from citrulline and aspartate, as discussed earlier in this article (Fig

Hamanaka RB, Chandel NS

PloS One (2014) 9(6):e99835

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Upon binding cytoplasmic DNA, it recruits RIP2 via its WD40 domain, activating NF-B-mediated inflammation

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