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Clinical assessment Clinical assessment was done using modified Hemi-Melasma Area and Severity Index (HEMI-MASI) to grade the severity of melasma before and after stoppage of treatment by two blinded independent dermatologists

6.2 Iodine insufficiency and preeclampsia: examining the connection Iodine deficiency constitutes the primary hypothyroidism etiology, with pregnancy-associated increases in renal iodine clearance and fetal iodine requirements potentially exacerbating maternal iodine insufficiency (Reische et al., 2021)

Acknowledgements Patent applications (EP25206946.3, P.449964) to protect the new composition have been filed

Verification: Third-party COA available

Proteoglycans, such as decorin and aggrecan, interact with collagen fibrils and contribute to the viscoelastic properties of the ligament