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In an openloop device, parameters (frequency, pulse width, duty cycle, etc.) are fixed and cannot automatically respond to changes such as impending seizure, fluctuations in inflammatory markers, or other biometrics

Such important mechanisms, nonetheless, fail to fully account for the in vitro and in vivo immunologic actions of DMF (39)

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Protein interaction network analysis To better understand how riboflavin deficiency might affect the protein expression profiles in HepG2 cells, a proteinprotein interaction network was generated