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Pyruvate Carboxylase Pyruvate carboxylase is the critical first enzyme in the conversion of pyruvate to glucose in the pathway of gluconeogenesis

Free Radic Biol Med 63:5164 Schrammel A, Gorren AC, Schmidt K, Pfeiffer S, Mayer B (2003) S-nitrosation of glutathione by nitric oxide, peroxynitrite, and (*)NO/O(2)(*-)

This technological breakthrough has rendered the molecular defect characteristics of tumor cells the groundwork for clinical diagnosis and treatment, significantly enhancing the scientific and precise nature of treatment plans

CRC is the third cause of cancer death worldwide

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