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From a pharmacokinetic perspective, studies indicate no evidence that the combination of Vitamins B1, B6, and B12 adversely affects the pharmacokinetics of each individual vitamin

For those with diagnosed deficiency, medical professionals may prescribe highdose B12 tablets (1,000 g) or intramuscular injections

doi: 10.1021/ja411046j

It rarely hurts and often helps
Pre-Supplementation Medical Evaluation Getting a medical check before starting B12 supplements is a must
