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A systematic review referencing 50 studies found that more than 28% of analyzed supplements contained undeclared performance-enhancing substances that could lead to inadvertent positive drug tests

William Murphy, who was co-honored with a Nobel Prize in 1934 for his discovery of liver as a very effective treatment for B12 anemia, remarked: I started one of my patients on liver therapy

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In the 1960s, Swedish investigators treated 64 patients with pernicious anaemia with 1000 g of oral cyanocobalamin, and all showed clinical and haematological remission [3]