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Akin to other neurodegenerative disorders, inflammation in the affected regions, such as the motor cortex and spinal cord, is driven by a complex interplay between genetic predispositions and environmental influences

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In addition to S1PR1, S1PR4 also plays a crucial role in mediating the S1P migratory effect on satellite cells (Calise et al., 2012)

Accordingly, in response to A

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