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In the case of redox stress, two molecules of GSH reduce one molecule of hydrogen peroxide in the presence of glutathione peroxidases, generating one molecule of glutathione disulfide (GSSG), an oxidized form of GSH, and two molecules of water [122, 123]

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A Brief History: From Abstinence-Only to Evidence-Based Pharmacotherapy The treatment of SUD has historically leaned heavily on abstinence and psychotherapy

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The future of antioxidant therapy likely lies in this integrative approachcombining targeted molecular hydrogen delivery through hydrogen-rich water with strategies to support endogenous antioxidant systems like glutathione reductase