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Besides, pyroptosis not only contributes directly to OA, but also interacts with other types of PCD, such as apoptosis, to promote osteoarthritis

The timely diagnosis of patients, coupled with intensive therapies that impose a considerable burden on the body [2], and the acceleration of aging in society [3], wherein the elderly demonstrate a heightened incidence of all cancer forms and the highest mortality rate [1], underscores the imperative for scientists to pursue novel, more efficacious, and less taxing therapies

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The biological effects attributed to this peptide appear to arise from its interaction with several interconnected physiological pathways

By age 30 the aging effects are already visible

their effects may be modulated by levels of riboflavin, choline, betaine, and vitamin B12, as well as by gene-gene interactions
