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Calma AD, van den Bos M, Pavey N, Santos Silva C, Menon P, Vucic S Physiological biomarkers of upper motor neuron dysfunction in ALS

Aliment Pharmacol Ther 2006

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DOI: 10.1196/annals.1320.010 Pennisi M, Malaguarnera G, Di Bartolo G, et al

In cases where the CSF-VDRL is nonreactive despite high clinical suspicion, CSF-Fluorescent Treponemal Antibody Absorption (FTA-ABS) or CSF-TPPA assays can enhance diagnostic sensitivity ( Radiologically, spinal neurosyphilis is typically characterized by long-segment T2 hyperintensity, predominantly affecting the dorsal columns, accompanied by myelitis-like changes and patchy enhancementfeatures notably absent in our patient

Together, they may produce metabolic improvements that exceed what either compound achieves alone
