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Predictors of primary response to biologic treatment [anti-TNF, vedolizumab, and ustekinumab] in patients with inflammatory bowel disease: from basic science to clinical practice

(Lausanne) 2018;9:402

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REGULATORY T CELLS Initial in vitro skewing experiments demonstrated that Treg cells have a lower glycolytic rate compared to their oxygen consumption rate, and FOXP3 expression increases mitochondrial oxygen consumption and ROS production (93)