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2 Low back pain and intervertebral disc degeneration Low back pain (LBP) is one of the most common clinical symptoms, significantly impacting individuals across broad populations (Hartvigsen et al., 2018

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injections of 100 nmol kg 1 MK-801 ( n = 8 rats), 100 nmol kg 1 GLP-1 ( n = 8 rats), 100 nmol kg 1 GLP-1MK-801 ( n = 8 rats) or vehicle (isotonic saline, n = 8 rats) for three consecutive days while being offered the choice between chow and kaolin