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The p53 protein, a key human tumor suppressor, regulates the expression of oncogenes and downstream signaling pathways, contributing to biological effects (7275): Beyond its role in cancer, p53 is highly expressed in the brain, where it influences dendritic growth, oxidative stress response, apoptosis and autophagy, making p53 dysfunction and associated pathways noteworthy in the pathogenesis of AD (7678)

Why IV delivery makes the difference: Your digestive system limits how much vitamin C you can absorb orally

[DOI] [PMC free article] [PubMed] [Google Scholar] 194.Zhang J., Cui H., Yin J., Wang Y., Zhao Y., Yu J., Engelhardt U.H

10.1002/cpdd.410 Neurology 160

Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-alpha

The biological significance of the variable composition of scavenging and repair enzymes in plastids during streptophyte evolution is yet unclear but raises the question if the only reason is functional redundancy, or if parallel redox cascades with coupling to different electron donors are important for processes such as stress signalling or relate to differences between tissues or light conditions