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Citrate exerts this effect through interaction with the muscle PFK-1 isoform (PFKM) inducing a shift from the glycolytically active tetrameric form to the catalytically inactive dimeric form

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AS-IV also regulates blood glucose and lipid metabolism through modulation of the gut microbiota

3), and discuss the recent preclinical studies targeting some of these processes

Mitochondrial A: A potential focal point for neuronal metabolic dysfunction in Alzheimers disease