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While some ingredients have promising research behind them, they dont replace medical treatment or address the root cause of more serious health concerns

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Since endogenous VEGF-regulated angiogenesis may not be sufficient to better balance angiogenesis for optimal tendon repair, the application of exogenous VEGF or anti-VEGF antibody delivery can also regulate the balance of pro- and anti-angiogenic factors

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Furthermore, regulatory approval requires case-by-case evaluation by authorities such as the FDA and European Medicines Agency, emphasising the need for manufacturing consistency and comprehensive safety evaluations [178]