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4.1 Antidepressants Depression affects approximately 300 million people worldwide and is a significant global health issue (Soek et al., 2021b)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Frederickson C.J., Hernandez M.D., Goik S.A., Morton J.D., McGinty J.F

The PI3K/AKT/mTOR pathway, affected in over 80% of type I ECs, presents both prognostic significance and therapeutic potential, with PTEN and PIK3CA mutations being key components (126)

Familial and second lung cancers: a nationwide epidemiologic study from Sweden