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In addition to the current mechanism of the effects of the MeDiet on the response to oxidation and inflammation, another candidate and potential neuroprotective mechanism might be associated with the roles mediated by this dietary pattern in regulating and/or protecting the gut microbiota composition of the gut-brain axis (7, 114)

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104 In particular, licorices main phytoestrogen, liquiritigenin, has demonstrated a substantially stronger binding affinity for ER-beta than ER-alpha 105,106

Bottom line on the preclinical class: it shows measurable effects in rodents over days of dosing-plus-training, the best of it is one clean independent study, and it tells you nothing reliable about if or when a human would notice anything

Unlike proteins, which are longer chains of amino acids, peptides are shorter and act more efficiently within the body

But update the diagnosis once the cause is confirmed.