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Injectable B12 bypasses absorption issues and is first-line treatment for malabsorption conditions, whilst oral doses of 1,0002,000 g daily may suit dietary deficiency without malabsorption

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According to the randomization procedure, Group 1 was assigned to the novel methylcobalamin nasal spray (NASO B12) and Group 2 was assigned to methylcobalamin oral tablet for the treatment of vitamin B12 deficiency during the study period of 15 days [Figure 1]