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Description
Similar associations have been reported in bipolar disorder and systemic lupus erythematosus, where individuals with severe BBB disruption had more extensive brain volume loss or greater psychiatric morbidity 50,51
B12 injections are clinically indicated for specific patient groups with confirmed deficiency or malabsorption conditions
Think of it like this: if your research protocol calls for a 250 microgram (mcg) dose, but your reconstitution math is off by 20%, you're not actually administering 250mcg
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However, typical research protocols use 250-500mcg once or twice daily, often injected subcutaneously near the injury site
2 In comparison with other B vitamins, B 12 is not synthesized by animals, fungi, or plants
