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High dose oral cobalamin would be a reasonable alternative as maintenance in patients unable to tolerate intramuscular injections provided there is good compliance with treatment
Open Med
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Best results are obtained if samples are quenched and ground in liquid nitrogen and then extracted directly into acid as the material thaws, taking care to homogenize regularly during this procedure
& Awan, S
Likewise, if too much OH is introduced into the system, carbonic acid will combine with it to create bicarbonate, lowering the pH
