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To test whether the special localization of ORF3a was important for its function in autophagy, different truncated ORF3a proteins were constructed and tested for their function in autophagy (Fig

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Thus, before MSC can be considered a reliable source for clinical replacement of dopaminergic cells, their ability to transdifferentiate terminally towards a neuronal lineage needs to be resolved and their mechanism of action following transplantation needs to be elucidated (Schwarz and Storch, 2010)

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Different routes of administration of glutathione including