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May be exacerbated by treatment

The B12 component remains the same regardless of indication

doi: 10.1038/nature14344 24 WallachDKangTBKovalenkoA

Microglia-specific overexpression of alpha-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity

For instance, it is important that the brain organoids are composed of more than one cell type (1) since some studies affirm that astrocytic mitochondria metabolize long-chain fatty acids more efficiently than neuronal mitochondria (Fecher et al., 2019)
