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This evidence is further supported in animal models of depression (Tuon et al., 2021)

The therapeutic effectiveness of herbal medicines is typically attributed to the synergistic interactions between multiple bioactive compounds, highlighting the importance of their standardization (175)

doi: 10.1186/s12870-020-02445-w 32 GulN.HaqZ

To achieve greater flexibility and adherence to metabolic switch with KD, different formulations have been developed over the past decades, with four main KD variants now widely accepted by researchers and physicians: Classic KD (CKD), Modified Atkins Diet (MAD), Medium Chain Triglyceride Diet (MCT), and Low Glycemic Index Therapy (LGIT) ( It is noteworthy that different types of KDs may have distinct effects on patient outcomes

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Dynamic balance among the respective components is necessary for BBB homeostasis