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a , Scheme of the in vitro sgRNA competition assay performed in HEK-293T SLC25A39 knockout cells expressing a vector control or SLC25A39 cDNA transduced with a pool of 5 control sgRNAs (sgControl, gray) and sgRNAs targeting TXNRD2 (pink) and SLC25A40 (green) (left)

PAPS/PAP ANTIPORTER IN CHLOROPLASTS Along with the BAT5, which exchanges 2-keto acids between chloroplast and the cytoplasm, the chloroplastidic transporter of activated sulfate (PAPS), which is essential for the sulfation of GSLs, flavonols, peptides, and other sulfated compounds in the cytoplasm has been recently identified ( Figures 1 and 2 , transporter 5)

Genetic disruption of the multifunctional CD98/LAT1 complex demonstrates the key role of essential amino acid transport in the control of mTORC1 and tumor growth
10.1016/j.ijbiomac.2019.09.232 [DOI] [PubMed] [Google Scholar] 22.Sasaki JI, Lu C, Machiya E, Tanahashi M, Hamada K
