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The involvement of OCTN1 in cancer metabolism, is probably unrelated to the poor ability of this transporter to mediate carnitine transport, however, it is interesting to know that OCTN1 is involved in the uptake of anti-cancer drugs (Table 1) such as Cytarabine (Zheng et al., 2016), mitoxantrone and doxorubicin (Okabe et al., 2008)

& Hejazi, N

Jimnez-CorteganaCIglesiasPRibaltaJVilario-GarcaTMontaezLArrietaFet al

[The clinical and hemodynamic effects of propionyl-L-carnitine in the treatment of congestive heart failure]

If left untreated, VHE can lead to coma and death

Chepkunov Dimitri
