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Its much less common in East Asian and African populations

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Maier EM, Liebl B, Roschinger W, Nennstiel-Ratzel U, Fingerhut R, Olgemoller B, et al

Thus, any injury requiring even limited immobilization and/or muscle disuse may have detrimental metabolic and functional consequences

10.1016/j.bbrc.2012.08.038 41

Unfortunately, research investigating the simultaneous experimentation with all three compounds has yet to be conducted