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Description
As a disadvantage, their use may be restricted in patients with diabetes mellitus or other clinical complications intensified by acidosis or ketosis [40]

Dermatology practical & conceptual, 8(1), 1521
Sex Med Rev

One major contributor is oxidative stress, which occurs when reactive oxygen species (ROS) cause cellular damage
The aglycone of ginsenoside Rg3 enables glucagon-like peptide-1 secretion in enteroendocrine cells and alleviates hyperglycemia in type 2 diabetic mice

Closure and Interpretation The clinician interprets clinicalresponse patterns, laboratorytrend data, and adverseevent profiles to determine whether isotretinoin is providing sustained acnecontrol without unacceptable toxicity, then adjusts dose, duration, or adjunctive therapies as needed
