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Hangauer et al., 2017

Report of two cases

Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism

Conclusion: Overall, this study sheds light on metabolic pathways that are dysregulated in tamoxifen-resistant cell lines and the potential role of each of these pathways in the development of resistance

This establishes baselines and identifies any changes that might warrant attention
