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CRBN-DDB1 is widely used in targeted protein degradation (TPD) and oncology research, it is essential for studying the mechanism of immunomodulatory drugs (IMiDs) and discovering novel PROTACs
They found that this combination not only promoted the transformation of WJMSCs into NP cells, but also prevented cell leakage during and after implantation, avoided complications, and achieved the effect of IVD repair by transplantation of stem cells
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