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These findings suggest that the initial GSH concentration has a limited effect on antioxidant capacity and the level of [ROS] in RP retinas

Zhai J, Bo Y, Lu Y, Liu C, Zhang L

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Activation of the NRF2 pathway, including induction of NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase-1 (HO-1), promotes autophagic clearance and restrains over-activation [87] (Fig

1 (2024): e14426

TLR2, which identifies a variety of bacterial products, including lipoteichoic acid, lipoproteins, peptidoglycans, and bacterial amyloids like curli protein, can be expressed in response to the GM (13) (Figure 3)