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Natural Killer (NK) Cells: Impaired cytotoxicity and dysfunctional immune surveillance have been observed in MCTD patients, exacerbating autoimmunity

doi: 10.1007/s00125-018-4614-2 25 HoraS.PahwaP.SiddiquiH.SaxenaA.KashyapM.SevakJ
doi: 10.1016/j.arcmed.2021.03.002 475 WangJHuangMDuYChenHLiZZhaiTet al

Cell Metabolism

The 2-ketobutyrate is converted to propionyl-CoA via the addition of Co-A catalyzed via branched-chain keto acid dehydrogenase (BCKD)

The research indicated that BCIcontrolled DBS was more accessible and could surpass traditional continuous neuromodulation in efficiency and effectiveness for PD [44]
