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The relative contribution of each system is different depending on the cell type, as discussed in the following section

Loss- and gain-of-function experiments with TMPO-AS1 were performed using the CCK-8 assay, transwell assays, clone formation assays, and xenograft models

(2009) Hyperglycaemia is associated with changes in the regional concentrations of glucose and myo -inositol within the brain

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This review highlights an urgent takeaway driven by two converging factors: (1) evidence-based dietary (and behavioral) habits are so critical to healthspan, and (2) brain development occurs early in life (Figure 1) and is crucial for long-term health