glutathione peroxidase 4 Mechanism of ferroptosis, (GPX4) glutathione Glutathione Peroxidase 4 (GPX4) (NM_001039848)

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Here the authors specifically examine deletion of a glutathione synthetic enzyme in the liver of adult mice and show that lack of glutathione affects lipid abundance through repressing NRF2.

No difference is shown in concentration of O2., H2O2, NO, ONOO, LPO, and GSH in the amniotic fluid, as well as in frequency of micronuclei in the amniotic fluid cells among investigated groups of pregnant women

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Dosing, side effects, regulatory status